Prolonged immune signaling can switch from fighting cancer to helping tumors grow by triggering changes that suppress the immune attack.

High-risk myelodysplastic syndrome, a bone marrow cancer that can turn into acute myeloid leukemia, is driven by stem cells that burn through an unusually large supply of one molecule: nicotinamide ...

The spread of cancer from a primary tumor to another place in the body, called metastasis, remains one of the greatest ...

High-risk neuroblastoma is one of the most aggressive forms of solid tumors affecting children, originating in the nervous system.

Cancer immunotherapy can lose its punch when tumor-fighting T cells become exhausted, but researchers may have found a way to keep them going longer. Scientists at Memorial Sloan Kettering Cancer ...

Tumors are not made up of cancer cells alone. They also contain immune cells and other support cells that interact within a ...

Repetitive sequences make extrachromosomal DNA vulnerable to breaks, which could be exploited for therapy — but might also promote tumour evolution.

Researchers at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center have identified a distinct type of prostate cell ...

Non-small-cell lung cancer (NSCLC) is the most common type of cancer affecting the lungs. The diverse types of NSCLC are characterized by cancer cells that grow and spread in different ways. The three ...

Cancer cells work together to source nutrients from their environment—a cooperative process that was previously overlooked by scientists but may be a promising target for treating cancer. "We ...