Endoreduplication is an alternative version of the classical cell cycle during which cells replicate their nuclear DNA without subsequently dividing, thereby increasing their ploidy level. This ...

Scientists have discovered that endoreduplication, which promotes cellular enlargement in the epidermal tissue of Arabidopsis thaliana, occurs randomly as a Poisson process throughout cellular ...

REISMAN, Zuelzer and Mitani 1 described polyploidy and endoreduplication of chromosomes in a patient being treated for acute leukemia. They ascribed these abnormalities to a primary chromosomal ...

c-Jun N-terminal kinase (JNK) is activated by diverse cell stimuli, including stress, growth factors, and cytokines. Traditionally, activation of JNK by stress treatment is thought to induce cell ...

The Fbw7/hCDC4 protein is the substrate specificity component of an Skp1–Cullin-F–Box ubiquitin ligase complex. Lesions in the Fbw7 gene have been observed in a large list of cancers (Moberg et al., ...