You should not take more than 1,200 milligrams of over-the-counter ibuprofen per day. If you take too much ibuprofen, it can cause serious side effects, including stomach problems and kidney damage.

So there I was at midnight, night after night, my neck pain screeching at a 10+++ on a scale of 10, popping ibuprofen by the handful, dutifully worrying about the well-known dangers of a ...

This story was originally published on April 18, 2025, and has been updated. On Monday, President Trump announced that the Food and Drug Administration would be discouraging the use of acetaminophen ...

Over-the-counter pain relievers can provide short-term relief for issues like headaches and muscle aches, but should not be used for more than a few days without consulting a doctor. It’s important to ...

Over-the-counter (OTC) pain medications are generally safe and effective, but daily or long-term use isn’t recommended. Several factors, including drug side effects and your medical history, can ...

Ibuprofen can interact with many medications, including this common antidepressant. We'll explain what you need to know if ...

Ibuprofen is one of the most widely used over-the-counter pain relievers and anti-inflammatory medications. While it’s effective for headaches, muscle aches, and fever, it’s not without risks when ...

When hit with a headache or fever, people often reach for over-the-counter painkillers like acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs) as their first line of defense. Used ...