While the anti-inflammatory effects of cannabinoids have been shown in previous studies, exactly how they exerted those effects remained unclear. Now, researchers from the Friedrich Schiller ...

A new study by researchers at Brigham and Women’s Hospital reveals the mechanisms behind severe inflammation in asthma. The findings demonstrate that prostaglandin E2 (PGE2), a naturally occurring ...

A new human study has uncovered how the body naturally turns off inflammation. Researchers found that fat-derived molecules called epoxy-oxylipins rein in immune cells that can otherwise drive chronic ...

Northwestern Medicine scientists have discovered a new mechanism that controls a specialized group of T-cells, known as regulatory T-cells, and may serve as potential therapeutic targets to treat ...

The key element in the mechanisms in question is tumor necrosis factor-α receptor-1, TNFR1, which becomes pro-inflammatory on binding to the cytokine TNF-α. In one of the situations analyzed, the ...

Chronic inflammation is acknowledged as the fundamental cause of various pathological conditions, and in recent decades, there has been a growing focus on ...

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus. In 2022, ...

A tightly regulated inflammatory response that is precisely turned on and then off is key for host protection against infection. However, in some instances, these pathways can be unnecessarily ...

A first-of-its-kind study has identified overactive inflammation and loss of critical protective mechanisms in the brain as potential contributors to suicide risk. The findings could lead to the use ...

GRAND RAPIDS, Mich. (WOOD) — A groundbreaking study at the Van Andel Institute has tied a link between overactive inflammation and loss of critical protective mechanisms in the brain as a potential ...

Obesity associated with hypothalamic dysfunction was initially described in patients with craniopharyngioma. Hypothalamic obesity may also result from brain radiation, infection (eg, tuberculosis), ...