The neuromuscular junction—where nerves and muscle fibers meet—is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of ...

The neuromuscular junction - where nerves and muscle fibers meet - is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of ...

Neuromuscular diseases are caused by problems in the way muscle cells, motor neurons, and peripheral cells interact. Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz ...

James F. Howard Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill, explains how nerve and muscle signaling in the neuromuscular junction go awry in myasthenia gravis.

ORLANDO, Fla.--(BUSINESS WIRE)--Hesperos, Inc. has increased its pioneering human-on-a-chip drug testing capabilities by adding a new in vitro, human-human neuromuscular model to its patented ...

The neuromuscular junction (NMJ) is a specialised synapse responsible for translating neuronal signals into muscle contractions, forming the basis of voluntary movement and postural control. Integral ...

The muscle transmembrane protein Vangl2 helps organize the development and maintenance of connections between muscles and motor neurons, a study concludes. A skeletal muscle isn’t much use without a ...

The neuromuscular junction is the synapse or junction of the axon terminal of a neuron within a muscle fiber plasma membrane. Several diseases involve the neuromuscular junction as the primary site of ...

Researchers have created a human-derived neuromuscular junction from a person with amyotrophic lateral sclerosis (ALS) with the goal of testing anti-ALS drugs that not only prevent neuronal death but ...

A recent review article titled "The Role of Rapsyn in Neuromuscular Junction and Congenital Myasthenic Syndrome" has been published by researchers from Nanchang University in China. Led by first ...

Congenital myasthenic syndromes (CMSs) are a heterogeneous group of disorders that affect the safety margin of neuromuscular transmission — the depolarization that is required for propagation of the ...

Frog neuromuscular junction fly-through. Shown in red is a large muscle fiber (diameter 50 micrometers) that is innervated by a myelinated axon colored in white. The interface between muscle and axon ...