The answer depends on the questions you’re trying to answer, as well as the origin, quantity, and quality of your samples. In this article, we’ll briefly discuss several RNA-seq workflows, how they ...

RNA-seq succeeded across all tumor types and tissue formats, including degraded FFPE samples. Researchers conclude that targeted RNA-seq can serve as a stand-alone molecular diagnostic with high yield ...

Precision molecular diagnostics aim to identify alterations providing diagnostic, prognostic and/or therapeutic information, with the goal of tailoring treatment to the specific molecular makeup of ...

Formalin-fixed paraffin-embedded (FFPE) samples represent a vast and valuable resource of patient material, often linked to extensive clinical history and follow-up data. However, achieving ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

Hypertrophic scars (HS) are abnormal outcomes of wound healing, marked by excessive extracellular matrix (ECM) deposition and ...

Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have documented their use of a new RNA sequencing technology to uncover molecular ...

Rapid precision run-on sequencing (rPRO-seq) may help doctors understand disease states and treatment response in real time. Researchers at Sylvester Comprehensive Cancer Center (FL, USA) have ...

The high complexity and diversity of the eukaryotic transcriptome poses significant challenges for the efficient detection of specific transcripts. Conventional targeted RNA-seq methods often require ...

LAUSANNE, Switzerland--(BUSINESS WIRE)--Alithea Genomics, a leader in the field of large-scale RNA sequencing and transcriptomics, announced today the launch of MERCURIUS™ Full-Length DRUG-seq library ...

Diabetic foot ulcer (DFU) is one of the most serious complications of diabetes and a major cause of lower-limb amputation.

Discover why animal models fall short in AI drug discovery and how human-first datasets and functional genomics are changing ...