Gifts and payments from pharmaceutical companies to doctors increase inappropriate prescribing and the number of prescriptions doctors write, and probably increase the costs. Pharmaceutical company ...

Stopping sedation each day may reduce the time people spend on a ventilator, probably reduces the number who die, and probably reduces the time people spend in intensive care and hospital, compared to ...

Compared with an inactive (dummy) treatment, aciclovir and penciclovir creams probably speed up cold sore healing by about one day without increasing the risk of unwanted events. Compared with each ...

Nicotine e-cigarettes, commonly known as vapes, are more effective in helping people quit smoking than many conventional methods such as nicotine gums and patches and quitting with behavioural support ...

LBP is very common. While most back pain gets better without medical treatment, about 10% of cases lasts for three months or more. There are many therapies that are used to treat the pain, and improve ...

Urinary incontinence is the leakage of urine when coughing or exercising (stress urinary incontinence) or after a strong uncontrollable urge to urinate (urgency urinary incontinence). In women who ...

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This review shows that in subacute (medium-term) or persisting neck pain, at closest to 12 weeks follow-up, massage compared to a 'dummy' massage probably results in little to no difference in pain, ...

Overweight and obesity are important public health problems and are associated with many serious health conditions. The risk of developing overweight and obesity depends on lifestyle factors such as ...

During an asthma attack, the airways (tubes in the lungs) narrow making breathing difficult. The initial response to an asthma attack is to treat with a drug that can open up the airways and make ...

Our Handbooks describe the process of preparing and maintaining diverse types of systematic reviews. Handbooks are updated regularly to reflect advances in systematic review methods and in response to ...

Dental implants can be placed in sockets just after tooth extraction (immediate implants) or after a couple of weeks up to a couple of months (immediate-delayed implants) or thereafter (delayed ...