Gifts and payments from pharmaceutical companies to doctors increase inappropriate prescribing and the number of prescriptions doctors write, and probably increase the costs. Pharmaceutical company ...

Stopping sedation each day may reduce the time people spend on a ventilator, probably reduces the number who die, and probably reduces the time people spend in intensive care and hospital, compared to ...

Compared with an inactive (dummy) treatment, aciclovir and penciclovir creams probably speed up cold sore healing by about one day without increasing the risk of unwanted events. Compared with each ...

Nicotine e-cigarettes, commonly known as vapes, are more effective in helping people quit smoking than many conventional methods such as nicotine gums and patches and quitting with behavioural support ...

There has been an increasing demand for whiter teeth. Home-based whitening products with a bleaching action have become popular and are prescribed to people by the dentist or purchased ...

You must have JavaScript enabled to use this form.

Dental implants can be placed in sockets just after tooth extraction (immediate implants) or after a couple of weeks up to a couple of months (immediate-delayed implants) or thereafter (delayed ...

This review shows that in subacute (medium-term) or persisting neck pain, at closest to 12 weeks follow-up, massage compared to a 'dummy' massage probably results in little to no difference in pain, ...

Compared to placebo, cold therapy may improve blood loss, pain, knee range of motion and short-term swelling after total knee replacement (TKR). We are less certain of its effect on blood transfusions ...

During an asthma attack, the airways (tubes in the lungs) narrow making breathing difficult. The initial response to an asthma attack is to treat with a drug that can open up the airways and make ...

- Methylphenidate might reduce hyperactivity and impulsivity and might help children to concentrate. Methylphenidate might also help to improve general behaviour, but does not seem to affect quality ...

Our Handbooks describe the process of preparing and maintaining diverse types of systematic reviews. Handbooks are updated regularly to reflect advances in systematic review methods and in response to ...