A 19-year-old woman presented with fever and cervical lymphadenopathy. The white-cell count was 2900 per microliter (reference range, 4000 to 11,000), and the lactate dehydrogenase level was ...

When public health measures conflict with cultural, relational, and emotional practices surrounding severe illness and death, they may lead to uprisings that increase the risk of infection spread.

A 2-month-old boy was brought to the ED after a seizure. The scalp hair was sparse and coarse. Serum copper and ceruloplasmin levels were markedly low. MR angiography showed tortuosity of the ...

For persons living with both type 2 diabetes and obesity, weight management may be the most effective therapy for type 2 diabetes. Glucagon-like peptide-1 (GLP-1) receptor agonists have potent ...

Though aspects of the U.S. Gold Standard Science initiative reflect valid standards, methodologic standards must be applied without selective use, political distortion, or erosion of scientific ...

In this phase 3, randomized, double-blind trial, we assigned adults with obesity without diabetes to receive a once-weekly subcutaneous injection of retatrutide (at a dose of 4 mg, 9 mg, or 12 mg) or ...

Settlements of lawsuits against opioid manufacturers and other entities will shape drug policy for decades. Attention is needed to ensure that the funds will be dedicated to evidence-based activities.

A new European Union regulation introduces a centralized clinical assessment process for comparing the effectiveness and safety of new medicines with those of the standards of care in various ...

Recently launched smart vaping devices provide financial incentives tethered to use or engagement metrics. The addictive potential of such devices poses public health concerns. Amanda M. Palmer, Ph.D.

When a robust long-time patient with chronic pain and heavy alcohol use declines precipitously after a complicated hospital course, her medical team must find a way to revive her old self.