Real-time RBQM requires proportionate analysis frequency matched to data arrival and issue criticality, not continuous reanalysis, because signal churn from over-frequent runs creates alert fatigue ...

In this video interview, Saamir Pasha and Carole Berini, PhD, of Ontada, explain how building trust into the data foundation—through source lineage, standardization, and reconciliation—is what makes ...

Radiopharmaceutical therapy is exposing a broader challenge for clinical development: scientific innovation can advance only ...

The FDA has published a Transparency Roadmap outlining its fiscal year 2026 milestones and fiscal year 2027 priorities across ...

A new request for information asks for comments on dose selection, safety monitoring, eligibility criteria, and oversight ...

In this Q&A, Claire Riches, VP of clinical solutions at Citeline, discusses how AI is transforming endpoint selection and protocol pressure-testing, what data inputs matter most for realistic ...

Site training effectiveness depends on readiness at first-patient-in, requiring learning-science design principles around performance focus, cognitive load reduction, progressive sequencing, and ...

In today's ACT Brief, we examine FDA input sought on early-phase ibogaine protocols, why mixed outsourcing models spread ...

Register Free: https://www.appliedclinicaltrialsonline.com/act_w/Operation-TrialBlazer ...

Mixed outsourcing models have moved from exception to mainstream as sponsors look to allocate resources more deliberately, ...

Radiopharmaceutical therapy is exposing a broader challenge for clinical development: scientific innovation can advance only as fast as the infrastructure, data, and cross-functional decisions ...

In today's ACT Brief, we examine practical guidance for clinical operations teams beginning AI adoption, how hierarchical ...