Hastie was recently named an LJI Research Assistant Professor. Her new lab will focus on “New World” Arenaviruses, a family of viruses that has become a growing threat in the Americas. These viruses ...

LJI Research Assistant Professor Sydney Ramirez, M.D., Ph.D. In 2024, Sydney Ramirez, M.D., Ph.D., changed the field of immunology. The problem was blood. Only a fraction of the body’s immune cells ...

At La Jolla Institute, our breakthroughs in immunology make Life Without Disease® possible.

At La Jolla Institute, our breakthroughs in immunology make Life Without Disease® possible.

Dr. Kawakami has been using the high-affinity IgE receptor (FceRI) signaling in mast cells as a model system. Following his co-discovery of two Tec family PTKs, Btk and Itk, in mast cells, his group ...

Virulent isolates of CMV encode the ul144 orf, and we identified UL144 as an orthologue of the herpesvirus entry mediator (HVEM), a member of the TNF receptor superfamily. When the immune checkpoint ...

Given their previous studies on crosstalks between PTKs-dependent and G protein-coupled receptor-dependent signals in FceRI-stimulated mast cells, they have been characterizing PLC-b isoforms. In ...

LJI Research Assistant Professor Parham Ramezani-Rad, Ph.D. “Almost everyone has heard of antibodies,” says Parham Ramezani-Rad, Ph.D. “Far fewer people know about the cells that make them. I think of ...

A collaboration with various centers of the Human Immune Profiling Consortium (HIPC) to build upon the existing infrastructure of ImmPort, a publicly-available data repository, which includes ...

Since their finding of ‘monomeric IgE effects’ on mast cell survival in 2001, Dr. Kawakami and associates have shown that IgEs exhibit a tremendous heterogeneity in their ability to induce mast cell ...

It is thought that an interaction between predisposing genes and environmental factors, such as viral infections, may trigger T1D. Several viruses, mainly from the Enterovirus genus have been ...